Dr. Manon Ranger conducts translational research, integrating preclinical investigations with clinical studies in preterm neonates undergoing intensive neonatal care to uncover mechanisms of vulnerability to early adversity (e.g. separation from the mother, stress/pain) in relation to brain development. She also investigates and tests methods to mitigate the adverse effects of these undesirable events. She seeks to expand the repertoire of nursing practice by conducting cross-disciplinary translational research that integrates laboratory and clinical studies, so that her work will have a direct impact for improving the health of the most vulnerable infants and their families.
While the birth of a child is a miraculous event, it can also be a highly stressful one — especially when the birth is premature. Preterm births are the leading cause of infant mortality worldwide, and preterm infants who survive are exposed to pain and stress — multiple medical procedures, separation from their mothers — during what is perhaps the most vulnerable period in their lives.
How do such experiences affect the neurological and behavioural development of these babies? What can be done to mitigate their negative effects? UBC nursing professor Manon Ranger is exploring these complex questions through animal models that mimic the neonatal intensive care environment, as well as through clinical studies involving children who were born very preterm.